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Don't sit still
Get up and stretch, pace while you read the papers -- do anything but sit at your desk all day.
Instead of emailing your co-worker, walk to her cubicle to talk face to face. On the phone with a client? Get up and pace around, advises Roberta Larson Duyff, MS, RD, FADA, CFCS. Give yourself a 5-minute break off every hour of working at your computer. Move around and you can burn up to 100 calories in an hour.